Modelling complex solution equilibria. II. Systems involving ligand substitutions and uncertainties in equilibrium constants derived from formation constants
نویسندگان
چکیده
منابع مشابه
CRITICAL EVALUATION OF EQUILiBRIUM CONSTANTS IN SOLUTION STABILITY CONSTANTS OF METAL COMPLEXES
متن کامل
Determination of Rate Constants and Equilibrium Constants for Solution-Phase Drug–Protein Interactions by Ultrafast Affinity Extraction
A method was created on the basis of ultrafast affinity extraction to determine both the dissociation rate constants and equilibrium constants for drug-protein interactions in solution. Human serum albumin (HSA), an important binding agent for many drugs in blood, was used as both a model soluble protein and as an immobilized binding agent in affinity microcolumns for the analysis of free drug ...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1990
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v90-338